// Copies a CellRange & pastes it using a RowID & A ColumnID to identify the target location, which will be located in another Worksheet, identified by the otherSheet object. All content will be pasted to the new location, but the content from the rows will be pasted into columns & the content of the columns will be pasted into rows.
Worksheet otherSheet = workbook.Worksheet[ 0 ]; 
 
worksheet.Cells[ "D4", "F12" ].CopyAndPasteTo( 15, 5 , PasteOptions.All | PasteOptions.Transpose, otherSheet );