Hi Dustyn, As far as making a cell enabled or disabled (ReadOnly) at runtime, the following example will definitely suit your requirements. But to change a cell's EditTemplate at runtime does not seems to be an easy task as EditTemplate property belongs to the entire column and not just a single cell. Anywayz have a look at the following example ...

I'm converting to the WPF DataGrid from the .Net WinForms version. The transition is killing me! One thing I've noticed right away is the GroupByHeader grouped value displays the underlying bound data, rather than the content from the CellContentTemplate. I'm running across this with the ComboBox using the DataTableDictionary examples.  The ...